RECENT:

• A Double-Blind, Randomized, Multicenter, Trial Evaluating the Efficacy and Safety of XXXX in Adults with Focal Seizures (07/2025-ONGOING)
• An Open Label Clinical Trial to Evaluate the Efficacy and Safety of XXXX in Adult Patients with Focal Onset or Primary Generalized Tonic-Clonic
  Seizures(05/2025-Ongoing)
• An Open-label Extension Study to Assess the Long-term Safety and Tolerability of Adjunctive XXX in Subjects with Inadequately Controlled
  Symptoms of Schizophrenia.
• 1-01/2026 -ongoing –A Phase 2, Multicenter, Randomized, Double-Blind, Parallel-Arm Study to Investigate the Efficacy and Safety of Adjunctive Treatment with Brenipatide in Delaying Time to Relapse
  Compared with Placebo in Adult Participants with Bipolar Disorder (RENEW-Bipolar-1)
• 2- 02-2026-ongoing A Phase 3, Multicenter, Randomized, Double-Blind, Parallel-Arm Study to Investigate the
  Efficacy and Safety of Adjunctive Treatment with Brenipatide in Delaying Time to Relapse
  Compared with Placebo in Adult Participants with Major Depressive Disorder (RENEWMDD-1)
• 3-04-2026-ongoing-A Phase 2 Multicenter, Double-Blind, Parallel-Arm Study to Investigate the Efficacy and Safety of Adjunctive Treatment with Brenipatide in Adult Participants with Schizophrenia (RENEWScz-1)
• 4-04-2026-ongoing-A Phase 3, Multicenter, Randomized, Double-Blind, Parallel-Arm Study to Investigate the
  Efficacy and Safety of Adjunctive Treatment with Brenipatide in Delaying Time to Relapse
  Compared with Placebo in Adult Participants with Major Depressive Disorder (RENEWMDD-2)